Research Articles
Achieving Cross-Laboratory Biomarker Reproducibility: A Strategic Framework for Researchers
This article provides a comprehensive framework for researchers and drug development professionals aiming to enhance the reproducibility of biomarker studies across different laboratories.
Nutritional Biomarker Analytical Validation: A Comprehensive 2025 Guide from Discovery to Clinical Application
This article provides a comprehensive framework for the analytical performance validation of nutritional biomarkers, tailored for researchers, scientists, and drug development professionals.
Ensuring Biomarker Stability During Storage: Evidence-Based Protocols and Fit-for-Purpose Validation
This article provides researchers, scientists, and drug development professionals with a comprehensive guide to contemporary methods for ensuring biomarker stability during storage.
Navigating Variability: A Researcher's Guide to Reliable Urinary Biomarker Measurement
Urinary biomarkers offer immense potential for non-invasive disease diagnosis and monitoring, but their day-to-day variability poses significant challenges for research and drug development.
Addressing Within-Person Variation in Biomarker Measurements: A Comprehensive Guide for Robust Research and Clinical Application
This article provides a comprehensive framework for researchers, scientists, and drug development professionals to understand, quantify, and mitigate the effects of within-person biomarker variation.
Strategic Timing: Optimizing Biomarker Sampling for Accurate Kinetics in Drug Development
This article provides a comprehensive guide for researchers and drug development professionals on optimizing sampling schedules for biomarker kinetic analysis.
Enhancing Biomarker Reliability in Free-Living Populations: Validation Strategies and Translational Applications
This article addresses the critical challenge of translating biomarker research from controlled laboratory settings to reliable application in free-living populations.
Correcting Systematic Error in FFQ Data: Advanced Strategies for Reliable Diet-Disease Research
Systematic measurement error in Food Frequency Questionnaire (FFQ) data presents a significant challenge in nutritional epidemiology and drug development research, potentially distorting diet-disease associations and reducing statistical power.
Precision in Practice: Controlled Feeding Study Protocols for Robust Biomarker Evaluation
This article provides a comprehensive guide to controlled feeding study protocols for the evaluation of dietary biomarkers, a critical tool for overcoming the limitations of self-reported dietary data.
Biomarker Panels for Dietary Pattern Assessment: From Discovery to Clinical Application
This article provides a comprehensive overview of the development, validation, and application of multi-biomarker panels for the objective assessment of dietary patterns.