Research Articles
Nutritional Biomarkers in Cohort Studies: Enhancing Precision, Overcoming Challenges, and Validating Diet-Disease Relationships
This article provides a comprehensive resource for researchers and drug development professionals on the application of nutritional biomarkers in cohort studies.
Metabolomic Profiling for Dietary Biomarkers: From Discovery to Clinical Application in Precision Health
This article explores the rapidly evolving field of metabolomic profiling for identifying objective biomarkers of dietary patterns.
Doubly Labeled Water: The Gold Standard for Validating Energy Intake in Human Metabolic Research
Accurate measurement of energy intake (EI) is fundamental to nutritional epidemiology, clinical trials, and metabolic research, yet self-reported dietary data are notoriously prone to misreporting.
24-Hour Urine Sodium and Potassium Biomarkers: A Comprehensive Guide for Clinical Research and Drug Development
This article provides a comprehensive resource for researchers and drug development professionals on the use of 24-hour urine collection for sodium and potassium biomarker analysis.
Statistical Methods for Biomarker Calibration Equations: From Foundational Concepts to Clinical Application
This article provides a comprehensive overview of statistical methods for developing and applying biomarker calibration equations, a critical process for ensuring data accuracy in biomedical research and drug development.
From Lab to Clinic: Developing Robust Dietary Biomarkers Through Controlled Feeding Studies
This article provides a comprehensive guide for researchers and drug development professionals on the process of discovering and validating dietary biomarkers using data from controlled feeding studies.
Regression Calibration for Dietary Measurement Error: A Comprehensive Guide for Biomedical Researchers
This article provides a comprehensive overview of regression calibration methods to address the pervasive challenge of dietary measurement error in biomedical research.
Advanced Literature Search Strategies for Biomarker Discovery: A Multi-Omics and AI-Driven Guide for Researchers
This article provides a comprehensive framework for conducting effective literature searches in the rapidly evolving field of biomarker discovery.
Nutritional Biomarker Validation: Principles, Pitfalls, and Future Directions for Research and Drug Development
This article provides a comprehensive guide to the principles of nutritional biomarker validation, tailored for researchers, scientists, and drug development professionals.
Beyond the Self-Report: Navigating the Critical Challenges in Dietary Assessment for Robust Biomedical Research
Self-reported dietary data, derived from instruments like 24-hour recalls and food frequency questionnaires, are foundational to nutrition science but are plagued by systematic errors that impede research and drug development.